Lisbon to Fusina (Venice)

Discover the world’s last colonial empire, turned bustling cosmopolitan city. Lisbon has dozens of Moorish castles, pastel buildings, and white sand beaches to explore. This Atlantic-coast city perfectly encapsulates Mediterranean charm with its wine, food, and architecture.

Get lost in the Western world’s oldest continuously inhabited city. Cádiz continues to charm travelers today with its romantic El Pópulo and Santa María districts, fresh seafood, and the Puertas de Tierra which divides the city into old and new. In Seville, stroll through the ancient city center or see a flamenco show followed by tapas and a glass of delicious wine or sherry.

See the wealth of historical treasures found in the coastal city of Màlaga. Once a major trading port, Màlaga has an eclectic mix of sites influenced by the Phoenicians, the Moors, and the Spanish.

From its ancient natural harbor where Phoenicians would trade to its Roman Empire heyday when it was known as the New Carthage, Cartagena’s enviable position on the Mediterranean has long made it one of the most important ports in Spain. The country’s Naval Headquarters is here, as are Dockyard Gate and Midshipman School. Discover ancient Roman ruins and Modernista buildings, the magnificent Concepcion Castle and a stunning City Hall.

Sunbathe in one of Spain’s most exhilarating cities. Valencia is vibrant town with dynamic nightlife, outdoor activities and sports, and its mezcla of architectural wonders. In Old Town, see everything from a 15th-century palaces, to recent wonders of modern art.

The island nation of Malta is a treasure trove of cultures. Valletta, its fortified main city, rises dramatically from the water. This “City of Knights,” a monument to the past, was founded in 1566 by the Grand Master of the Knights of St. John. Sights not to be missed include the Magisterial Palace and St. John’s Cathedral, which is lavishly decorated with the coats of arms and banners of the crusading knights. Beyond Valletta, the countryside, although austere and rocky, has a special charm. Malta provides an enduring fascination for all visitors.

The island nation of Malta is a treasure trove of cultures. Valletta, its fortified main city, rises dramatically from the water. This “City of Knights,” a monument to the past, was founded in 1566 by the Grand Master of the Knights of St. John. Sights not to be missed include the Magisterial Palace and St. John’s Cathedral, which is lavishly decorated with the coats of arms and banners of the crusading knights. Beyond Valletta, the countryside, although austere and rocky, has a special charm. Malta provides an enduring fascination for all visitors.

Chania is a city on the northwest coast of the Greek island of Crete. It’s known for its 14th-century Venetian harbor, narrow streets and waterfront restaurants. At the harbor entrance is a 16th-century lighthouse with Venetian, Egyptian and Ottoman influences. Opposite, the Nautical Museum has model ships, naval objects and photographs. The former monastery of St. Francis houses the Archaeological Museum of Chania.

Rich with natural beauty and colorful history, Rhodes represents one of the most architecturally varied locations in Europe. Hellenistic, Byzantine, Medieval and Turkish influences intermingle with abundant sunshine and dry air to cast a magnificent light over the island that the ancients dedicated to Apollo, the God of Light. High on a cliff, the ruins of the Temple of Athena sit amidst the beautifully preserved Acropolis at Lindos.

Alovely seaside resort town on the Aegean coast, Kusadaşi is famous for sparkling waters, sandy beaches and enticing shops filled with designer clothing and hand-woven carpets and leather goods. More than these modern trappings, it is the gateway to Ephesus – the UNESCO-listed, 4,000 year old city – as well as the Temple of Artemis (one of the Seven Wonders of the Ancient World), Basilica of St. John, and House of the Virgin Mary.

For poets, Istanbul, next to Venice and Rome is the loveliest city in Europe and one of the most splendid in Asia. It is the only city in the world spread over two continents, separated by the Bosphorus. Istanbul was founded by Greek scouts in 660 BC and later became capital of the Roman, Byzantine and Ottoman empires. With its 3,000 years of history behind, it has always been the meeting point of East and West. It is a city filled with wonders of architecture and monuments to the faiths that inspired them. Formerly known as Byzantium, then Constantinople, its mosques, minarets and museums span two continents where the Bosphorus divides Asia from Europe. This strategic position has assured Istanbul’s status as a crossroads for trade and cultural exchange during the centuries. Must-see attractions include the dazzling treasury in Topkapi Palace and exquisite buildings of timeless beauty such as the Blue Mosque and Basilica of St. Sophia. Even those who are not avid shoppers will be enticed by the colorful sights and sounds of the world’s largest bazaar.

For poets, Istanbul, next to Venice and Rome is the loveliest city in Europe and one of the most splendid in Asia. It is the only city in the world spread over two continents, separated by the Bosphorus. Istanbul was founded by Greek scouts in 660 BC and later became capital of the Roman, Byzantine and Ottoman empires. With its 3,000 years of history behind, it has always been the meeting point of East and West. It is a city filled with wonders of architecture and monuments to the faiths that inspired them. Formerly known as Byzantium, then Constantinople, its mosques, minarets and museums span two continents where the Bosphorus divides Asia from Europe. This strategic position has assured Istanbul’s status as a crossroads for trade and cultural exchange during the centuries. Must-see attractions include the dazzling treasury in Topkapi Palace and exquisite buildings of timeless beauty such as the Blue Mosque and Basilica of St. Sophia. Even those who are not avid shoppers will be enticed by the colorful sights and sounds of the world’s largest bazaar.

While Çanakkale is a lively Turkish metropolis with an interesting mix of European and Asian influences, the city’s main appeal is its proximity to two important sites: the ruins of Troy and the battlefields of Gallipoli. Yes, this is the Troy made famous by Homer’s epic poem The Iliad and the ancient city where the legendary Trojan War took place. Today, the archaeological site is a UNESCO World Heritage Site and national park, complete with layers of ruins and a reconstructed wooden horse. On the opposite bank of the Dardanelles Strait, on which Çanakkale is located, are the Gallipoli battlefields. Extensive World War I battles were fought here, making the peninsula hallowed ground for the Turks and a commemorative site for the Allied Forces. Numerous monuments pay homage to lives lost, including the Monument of Martyrs erected to honor fallen Turkish soldiers.

Thessaloniki is a Greek port city on the Thermaic Gulf of the Aegean Sea. Evidence of Roman, Byzantine and Ottoman history remains, especially around Ano Poli, the upper town. The ruins of Roman Emperor Galerius’ 4th-century palace include the Rotunda that has been both a church and a mosque. Much of the city center was destroyed in the Great Fire of 1917. The rebuilt 20th-century city has a modern European layout.

Volos is a coastal port city in Thessaly situated midway on the Greek mainland, about 330 kilometres north of Athens and 220 kilometres south of Thessaloniki. It is the sixth most populous city of Greece. It is the capital of the Magnesia regional unit of Thessaly Region.

Mykonos, a former 18th-century pirates’ bastion, is now a sophisticated and cosmopolitan island resort. This quintessential Greek island offers a maze of winding streets, graceful windmills, inviting beaches, domed churches and whitewashed houses accented in blue. Dotting the waterfront are cafés, taverns and tempting shops.

Venture through Greece’s largest port city, Piraeus, as you make your way to the cradle of Western culture and the birthplace of democracy. Athens, among the world’s oldest cities with a history spanning 3,400 years, has long been the location of myth and muse, and its ancient heritage is still an incredible source of inspiration. Here, the Acropolis crowns the city as home to the Parthenon and other legendary temples and monuments.

Of all the Cyclades Islands, Santorini is often considered the most dramatic. Once an active volcano, it was known as Stongyle, or the Round Island. In about 1500 BC, the volcano erupted with such force that the center of the island literally exploded, leaving the haunting submerged crater into which Crystal Serenity sails. The island’s small villages were preserved in the ashes and recent excavations have uncovered a fascinating view of everyday life from 3,500 years ago. Santorini’s dark landscape offsets its simple, yet refined Cycladic buildings, which glimmer in the sunlight. The rich volcanic soil is ideal for grapes and the local vines produce a cherished crop known for its “special volcanic taste.” Thíra, or Fira Town, is laid out along the edge of a cliff that partially forms the rim of the now extinct caldera. A picturesque site, it exudes charm and an atmosphere of leisure that can be attributed to the easy-going Greek lifestyle.

Tethered to southern Greece’s mainland village of Gefyra by a causeway, Monemvasia rises above the sapphire-blue waters of the Aegean Sea looking like a giant slab of rock, and is often called the Gibraltar of the East. Its medieval Lower Town, encircled by ancient fortress walls, boasts an array of shops and restaurants. Crowning the islet is the Upper Town, offering stunning views of the surrounding area. It is also home to the 12th-century St. Sophia Church.

While the Katakolon’s main street is just a five-minute walk from the pier, you will probably want to venture farther out to see the ancient site of Olympia, the storied place where the Olympic Games originated in 776 BC. A look at the impressive monuments, including the Temple of Zeus, the Temple of Hera and the famous stadium, along with a visit to the nearby Archaeological Museum, offers a fascinating introduction to the Games and ancient mythology. Back in town, stroll the oceanfront walkway, relax over ouzo in an open-air café, or engage in a friendly round of haggling for jewelry and handcrafts, a modern-day sporting event that enjoys widespread popularity.

Shaped like a scythe, the island of Corfu is considered one of the Mediterranean’s best-kept secrets. Its lush interior is covered in cypress and olive trees while the main downtown area has elegant Venetian architecture and a serene atmosphere. Strategically important due to its location, this island has managed to maintain its uniqueness despite numerous invasions by outside forces. Today, the culture of Corfu reflects its turbulent past as well as its origins.

Though it has only recently re-emerged as an independent nation, Croatia is by no means a new country. There were settlements along the Dalmatian Coast before recorded time. When Slavic people migrated here in the 6th century, they converted to Catholicism and adopted the local Latin alphabet. The region eventually became part of the powerful Kingdom of Croatia. Medieval Dubrovnik, formerly the Republic of Ragusa, was one of several walled cities established in the 7th century to guard the coastal approaches. Its fortification was completed in the 13th century and has remained relatively unchanged. The city walls are in excellent condition and today prevent invasion by automobiles. Within the walls, the lovely sleek lines of Venetian-style buildings complement a wealth of ancient stone architecture. Nearby islands feature beautiful beaches as well as intriguing ancient ruins.

Fall in love with the charming Croatian town of Trogir where you can stroll through well-preserved medieval architecture, dine with stunning waterfront views or sail through the turquoise waters of the mountainous coast.